Yixin Bao, from The Second Affiliated Hospital of Jiaxing University in China, and colleagues examined psychiatric comorbidities among epilepsy patients. Seventy patients were included in the study and were classified as having either epilepsy with psychiatric comorbidities or epilepsy without psychiatric comorbidities. However, a significantly higher prevalence of structural brain abnormalities and increased occurrence of interictal epileptiform discharges were seen in epilepsy patients with versus without psychiatric comorbidities. "Epilepsy patients with psychiatric comorbidities show more brain abnormalities and epileptic discharges but no significant cognitive decline, highlighting the need for comprehensive evaluations and dynamic monitoring for early intervention," the authors write. More information: Yixin Bao et al, Epilepsy With Psychiatric Comorbidities Unveils Prominent Temporal-Lobe MRI Lesions and Elevated Frontotemporal Interictal Discharges, Journal of Craniofacial Surgery (2025).