The Brief Joe Mixon, last season's leading rusher for the Texans, will miss the first four games due to a non-football injury. The team will rely on Nick Chubb, Dameon Pierce, rookie Woody Marks, and Dare Ogunbowale to support their rushing attack. The Houston Texans announced Monday that running back Joe Mixon will miss the first four games of the regular season due to a non-football injury. HOUSTON, TEXAS - OCTOBER 27: Joe Mixon #28 of the Houston Texans reacts during the first half against the Indianapolis Colts at NRG Stadium on October 27, 2024 in Houston, Texas. Image 1 of 3 ▼ HOUSTON, TEXAS - AUGUST 16: Nick Chubb #21 of the Houston Texans carries the ball carries the ball during first half of the NFL Preseason 2025 game between Carolina Panthers and Houston Texans at NRG Stadium on August 16, 2025 in Houston, Texas.