This makes it very quick and easy to generate plots such as Figure 1, showing that when aligning unrelated/independent sequences Edlib for unit-cost alignments is around \(30\times\) faster than any affine alignment that includes a gap-open cost. Besides global alignment, another very relevant problem is semi-global alignment, where one sequence is aligned to a subsequence of another sequence. WP7: semi-global alignment This will be an incremental paper that compares A*PA to other aligners for mapping and semi-global alignment.