This time, however, the situation feels a bit more dire, as Notre Dame sits at 0-2 without any margin for error. Notre Dame will not need their A-game to beat in-state rival Purdue. Prediction: Notre Dame: 49, Purdue: 17Chris DaileyNotre Dame went on a run to the national championship after losing to Northern Illinois just a season ago. It remains to be seen whether the Notre Dame defense could even stop a nosebleed. Prediction: Notre Dame: 52, Purdue: 23Tyler ReidyI’m still in “I’ll believe it when I see it” mode with the Notre Dame defense, even in a matchup against lowly Purdue.