In fact, Michelle Hagen, a senior flavorist at Givaudan, the world's largest fragrance and flavor company, told Gastropod that, despite the cost savings, she hasn't used a single artificial chemical in her flavorings for the past four years—because the companies she mostly works with know that customers are turned off when they see that word on a label. In the past, the mention of "edible yeast" in the FDA definition of natural flavors typically referred to savory yeast extracts; now, designer yeasts are beginning to pump out vanilla, saffron, and even grapefruit flavors.