Liver function affects milk production Proper liver function has a positive effect on cow’s early milk production23 May 2024 23 May 2024 2 minute read 2 minute read By: By: Chris Wright North AmericaThe liver functionality index (LFI) is a marker that measures how well the cow's liver is working, and it could be a determinative tool during the transition period. The variables studied were weight loss at 28 days, milk production at 7 (initial), 28, and 100 days, ovary and follicle size, and days to first heat. However, cows with positive LFI had higher initial milk production, (P = 0.07) and 28 days (P > 0.05) but not at 100 days (P > 0.05). Initial milk production was statistically different (P < 0.001) and positively correlated with milk production at 28 (r = 0.80) and 100 days (r = 0.41). In contrast, positive LFI increased ovary (P < 0.05) and follicle (P < 0.05) size for both transverse (T) and longitudinal (L) compared with negative status.