Note: For context, please see this article on the Economist Job. This is a condensed and updated version of my earlier post On the pan-genome. Towards a multi-stranded genome Given that the completion of the human genome project was announced in 2003, one could be forgiven for thinking the kinks would have been worked out by now. It turns out however that as published today, the human DNA reference sequence is neither complete nor a good description of mankind.