Arizona is a 32.5 point favorite over Weber State with an over/under of 56.5 according to the FanDuel Sportsbook. Weber State lost 45-10 as a 26.5 underdog in its season opener at James Madison. Weber State was outgained 458-148 against James Madison and had three turnovers to two for the Dukes. Arizona should dominate Weber State on the line of scrimmage and make it difficult for the FCS Wildcats offensively. Based on how Weber State played versus James Madison, Arizona should cover the 32.5-point spread.