Arizona will kick off at Iowa State at 4 PM Mountain Standard Time on ESPN on September 27 as announced on Monday. The game at Iowa State is the third for Arizona on national television with a prime kickoff in 2025. Arizona at Arizona State, which will be televised by Fox, is the only other network designation remaining on the Wildcats' schedule. Arizona and Iowa State are both off on Saturday before they play what could be a key game in the Big XII. Iowa State began the season with a 24-21 win over Kansas State in Dublin, Ireland, during week zero.