So, yeah, those pretty little pomegranate seeds are definitely healthy. “The antioxidants in pomegranates help reduce free radical damage, including damage to the cells in the brain, contributing to overall health and support for brain function,” Zhu explains. While more complicated digestive conditions, like Crohn’s disease or irritable bowel syndrome, require medical treatment, pomegranate juice might reduce inflammation in the gut, she says. Even though juice gets lots of side-eye, pomegranate juice packs some serious perks. What should I do with pomegranate seeds to make the most of that sweet, sweet nutrition?