Lyme disease, despite impacting roughly 476,000 people every year, according to the Centers for Disease Control and Prevention, is still so misunderstood. But Lyme disease is real and the symptoms can be debilitating. Yet, disease-carrying ticks are present throughout the world — and when Lyme disease is left untreated, it can cause health issues that linger for years. Educating others about the risks of Lyme disease could save them years of painful symptoms and long-term effects. Check out these celebs who have all opened up about their experiences with Lyme disease.