The goal of the study was to examine through a systematic review and meta-analysis whether dental antibiotic prophylaxis affects the risk of PJIs. Researchers searched electronic databases for studies involving adults with total joint arthroplasties who underwent dental procedures, with or without antibiotic prophylaxis, they wrote. Dental procedures included any treatment involving gingival manipulation, such as routine cleanings. The incidence of PJIs after dental procedures ranged from 0.07% to 0.3% in patients given antibiotic prophylaxis and 0.07% to 0.18% in those without it. There was also no observed heterogeneity, supporting the conclusion that antibiotic prophylaxis before dental work does not reduce PJI incidence.