People with hemophilia A don't have enough clotting factor VIII (factor 8). Hemophilia BThis type of hemophilia (also known as Christmas disease) occurs when people don't have enough clotting factor IX (factor 9). For every 100,000 males, about 4 have hemophilia B.Hemophilia CThis rare type happens when people don't have enough clotting factor XI (factor 11). Clotting Factor ReplacementThe main treatment for hemophilia involves replacing the missing clotting factor. Internal bleeding: Bleeding in your internal organs can be life-threatening.