Diabetes mellitus, a condition affecting millions worldwide, is increasingly recognized as a significant risk factor for cognitive decline and dementia. More recently, the term “diabetes-associated cognitive decline” (DACD) has been proposed to encapsulate the range of mild to moderate cognitive impairments associated with diabetes. “Our findings emphasize the need to consider diabetes as a potential risk factor for dementia. These include:Glucose metabolismInsulin resistanceInflammationComorbid depressionVascular diseasesAdditionally, changes in adipokines, neurotrophic molecules, and Tau protein levels have been observed in diabetic patients experiencing cognitive decline. A Little on DiabetesType 2 diabetes is the most common form of diabetes and is also known as lifestyle diabetes.