A comprehensive meta-analysis, published in the journal Obesity Research & Clinical Practice, has shed light on the potential benefits of zinc supplementation in managing blood sugar levels among overweight and obese individuals. The findings were significant: zinc supplementation led to notable improvements in these health markers, suggesting a crucial role for zinc in enhancing blood sugar control. Interestingly, zinc supplementation alone significantly decreased FG and HOMA-IR, but not when combined with other supplements. This finding suggests that zinc’s efficacy in lowering blood sugar levels might be more pronounced when taken independently. This meta-analysis presents zinc supplementation as a potentially beneficial intervention for blood sugar control in overweight and obese individuals.