The U.K.’s Medicines and Healthcare Products Regulatory Agency said there’s no evidence that paracetamol causes autism and said it remains safe during pregnancy. “We found that there was about a 40% increased risk of autism without acetaminophen,” she said. A small number of women reported using ibuprofen for fever during pregnancy. Acetaminophen remains widely recommended because aspirin carries a risk of Reye’s syndrome and ibuprofen isn’t considered safe later in pregnancy. Vaccination before and during pregnancy, when indicated, remains one of the best safeguards against infections that trigger fever, she added.