India: 1% phytic acid is a suitable irrigating solution compared to 17% EDTA, as it causes less demineralization of radicular dentin. Both irrigants caused some demineralization, but the effect of phytic acid was significantly less. Phytic acid effectively maintained the structural integrity of root canal dentin. Within the study’s scope, 1% phytic acid emerges as a promising alternative to 17% EDTA, balancing effective canal irrigation with minimal structural impact on radicular dentin. Assessment of calcium ion loss and its effect on microhardness of root canal dentin using 1% phytic acid and 17% EDTA: An in vitro study.