South Florida-based board-certified dermatologist De Anne Harris Collier, MD, concurs, adding that research has shown that repair of DNA-damaged skin cells peaks, skin cells turn over more quickly, meaning increased rates of skin blood flow and skin permeability at night. In addition to testing each and every product that’s included in each and every review, we rely on experts who shape their fields, including dermatology, cosmetic chemistry, and medicine, to help us vet the ingredients and formulas. For our list of the best night creams, we considered each product’s performance across five primary categories: product ingredients and efficacy, packaging, fragrance, texture, and product wear.