The U.S.’ expanded tariffs under the second Trump administration are reshaping global supply chains by imposing steep, targeted duties and pressuring Asian economies to invest in American production. Firstly, the U.S. appears determined to reduce China’s dominance in global supply chains by building its own systems and reducing China’s importance in other economies’ manufacturing activities. In other words, a massive reshuffling of supply chains is underway, with consequences for companies all over the world, especially multinationals. Another key factor behind the reshuffling of supply chains are the closer relations between Southeast Asia and China, with increased cooperation in research, production, and distribution capabilities. The U.S. tariff regime is reshaping Asia’s economic landscape, particularly the structure of supply chains, with large shifts from one country to another.