“The fastest results come when we approach melasma on four fronts: suppress melanocytes, exfoliate pigment, reduce inflammation, and block UV/heat triggers,” says Dr. Khalifian. In addition to testing each and every product that's included in each and every review, we rely on experts who shape their fields, including dermatology, cosmetic chemistry, and medicine, to help us vet the ingredients and formulas. For our list of the best products for melasma, we considered each product's performance across five primary categories: product ingredients and efficacy, packaging, fragrance, texture, and product wear.