The Detroit Lions’ running back room has been under a spotlight all offseason, with plenty of changes shaping the unit coming into the 2026 NFL campaign. The unit endured the loss of David Montgomery in free agency, bringing in two-time Super Bowl champion Isiah Pacheco to fill the void before inking Jahmyr Gibbs to a long-term deal over the weekend. Lions RB Isiah Pacheco sprained his MCL, but HC Dan Campbell believes his running back should be ready for the regular-season opener. | USA TODAY Network via Reuters ConnectThe Lions’ running back room is thin behind its two-headed monster of Gibbs and Pacheco. Despite slotting in at RB2, Pacheco should see a safe volume for fantasy, making him a solid plug-and-play option at flex as a likely RB3 in fantasy lineups.