• p53 can adopt at least 50 different three-dimensional structures and is much more ordered than was previously thought. Order versus disorder: two classes of proteinsLike all proteins, p53 is built of a long chain of amino acids. Protein dynamics across many time scales, spanning seven orders of magnitudeProteins are very small and move extremely fast. They discovered structural dynamics that were far more diverse and complex than previously thought: Depending on the timescale at which p53 was observed, the protein showed very different dynamics. More stable structures than expected“p53 surprised us by forming stable three-dimensional structures even without a binding partner protein.