Despite extraordinary advances in biomedical science, neuropsychiatric disorders continue to impose one of the largest health burdens on societies worldwide. Against this backdrop, a new international journal, Neuropsychiatric Research, has been launched to focus on the increasingly blurred boundary between neurological and psychiatric medicine. Its inaugural editorial, titled “A New Journal in Neuropsychiatric Medicine—Illuminating the Brain–Behavior Interplay for Mental and Neurological Health,” was published on July 23, 2026. By bringing these fields together, neuropsychiatric research may help identify shared mechanisms and therapeutic targets across conventional disease categories. The journal also emphasizes open-science practices intended to make neuropsychiatric research more reliable and reproducible.