Men diagnosed with azoospermia are told, in effect, that a laboratory looked at their semen sample and found no sperm. Systems combining high-speed microscopic imaging, machine learning, and microfluidics can scan millions of images from a single sample and flag cells that a human technician would not find in a realistic timeframe. Azoospermia and the Search That Precedes TreatmentAzoospermia means no sperm is detected in the ejaculate on repeated analysis. Conventional laboratory practice involves spinning a sample in a centrifuge and having trained technicians manually inspect it under a microscope. Columbia reported the first clinical pregnancy using STAR in a research letter published in The Lancet, describing a single patient.