Best MLB betting sitesBelow is a quick comparison of some of the best options for sports betting sites for the MLB across the US. MLB betting - season overviewThe MLB offers betting opportunities every day throughout its 162-game regular season, several points in the calendar stand out for bettors. How we rate MLB sportsbooksLicensing and regulation (state-by-state): MLB betting sites must be fully licensed and regulated to operate in a given state before we give them our seal of approval. Responsible gambling: The best MLB betting sites provide tools to help bettors stay in control when gambling. Sports betting app: MLB betting sites also need a dedicated betting app that performs well on iOS and Android devices.