The Osteosarcoma Institute (OSI) provides research grants to nonprofit and charitable institutions worldwide for innovative osteosarcoma research, including clinical trials, correlative science, preclinical/translational research, and high-risk/high-impact projects. The Osteosarcoma Institute (OSI) supports research designed to accelerate progress in the prevention, diagnosis, treatment, and understanding of osteosarcoma. Clinical Trials GrantsClinical Trials grants support early-stage clinical studies designed to improve treatment outcomes for patients with relapsed or refractory osteosarcoma. Common Mistakes to AvoidChoosing the Wrong Grant CategoryMake sure the project matches the objectives of the selected OSI grant type. ConclusionThe Osteosarcoma Institute Grant Program provides significant funding opportunities for researchers working to improve the understanding and treatment of osteosarcoma.