Assistant professor and Presidential Frontier Faculty member Fanfei Meng is developing a nanoparticle-based drug delivery system that combines antibacterial treatment with immune regulation. The project reflects a broader shift in biomedical research toward computational methods capable of finding relationships within large, complex datasets. The challenge is that many physical features of sickle cell disease overlap with symptoms commonly used to identify depression. A screening instrument designed around the experiences of people with sickle cell disease could help clinicians separate psychological symptoms from disease-related physical effects, identify patients who need further evaluation and support more timely care. Subject of Research: Sepsis treatment, nanomedicine, drug delivery, artificial intelligence for Alzheimer’s disease and related dementias, and depression screening in sickle cell disease.