For a Notre Dame offense that has a bit of a reworked offensive line, although the expectations are high, this unit will call for things to perhaps have to be in a better place than is normally expected for an opener. Nov 15, 2025; Pittsburgh, Pennsylvania, USA; Notre Dame Fighting Irish quarterback CJ Carr (13) calls an audible at the line of scrimmage against the Pittsburgh Panthers during the fourth quarter at Acrisure Stadium. Nick Shepkowski's Week 1 Notre Dame vs Wisconsin PredictionDespite a slow start on offense, I fully expect Notre Dame's defense to control Wisconsin and never really have this game feeling much in jeopardy. It might not be a rout on the scoreboard that some hope for (the spread is roughly three touchdowns), but I don't expect Notre Dame to have to escape Lambeau Field with a victory by any means. Nick Shepkowski's Prediction: Notre Dame 31, Wisconsin 13