The pickup truck game has changed massively in the modern era, with models like the Ford F-150 remaining top sellers even alongside SUVs. Identifying the most reliable trucks of all time means looking directly at real-world tear downs and survival rates. The J35 3.5-liter V6 engine achieved legendary status for running well past 300,000 miles with basic timing belt maintenance. For many, the 2.3L manual transmission configuration makes a strong case for the most reliable truck ever made in the compact class. Still, the truck solidifies GM during this era as a most reliable truck brand contender.