Persistent fatigue and unexplained weight loss often get written off as consequences of ageing, but this assumption could be costing lives. But according to a cancer specialist, they are among the signs people too often ignore before seeking help from a doctor. Most ongoing symptoms have a harmless explanation, but it's important not to dismiss any symptoms that are persistent or unexplained. Cancer cases in the nation have reached a record high, with more than 403,000 people now diagnosed every year, according to Cancer Research UK. He continued: "There are many possible explanations, including anaemia, thyroid disorders and poor sleep — but persistent fatigue should always be discussed with your GP if it isn't improving."