The results indicate that people with high Lp(a) may benefit from more aggressive efforts to reduce other heart disease risk factors. It resembles LDL, often called "bad" cholesterol, but includes an additional protein that may make it more likely to contribute to cardiovascular disease. They can increase cardiovascular risk even when more familiar cholesterol measurements fall within normal ranges. Participants were divided into groups according to their Lp(a) levels (<75, 75-125, 125-175, or ≥ 175 nmo/L) and according to whether they already had heart disease. The association was also stronger among participants who already had heart disease (HR 1.30, 95%CI: 1.07-1.57) than among those without existing heart disease (HR 1.18, 95% CI: 0.91-1.54).