Therefore, the prospective observational study monitored 59 adult patients with chronic plaque psoriasis over 12 weeks at a tertiary center to evaluate the primary endpoints of sleep quality and insomnia changes using the Pittsburgh Sleep Quality Index (PSQI), the Insomnia Severity Index (ISI), and the 5-D Itch Scale. Quality Enhancements: Poor sleep quality, which initially troubled 10.2% of the participants, was successfully reduced to 5.1% through the consistent application of standard therapeutic regimens. Disease Severity: Higher baseline scores on the Psoriasis Area Severity Index were strongly associated with the presence of insomnia (P < 0.001), suggesting that more extensive skin involvement directly compromises sleep. The results suggest that standard non-biological treatments, which are essential in resource-limited settings, are highly effective in mitigating sleep disorders, as evidenced by clinical insomnia rates dropping to 3.4% and poor sleep quality being halved by the study's conclusion. ReferenceHazarika N, Bhatia R, Sarkar N, Vasisht S, Kansal NK, Gupta R. Sleep disorders in psoriasis and the effect of treatment on sleep quality: A prospective study in a resource-poor setting.