For some time now, there has been talk about democratising clinical trials. Suddenly faced with the logistical challenge of supporting devices with clinical-grade accuracy at “real world” sites without clinical infrastructure, many sponsors found those devices just weren’t feasible in a trial context. Consumer devices are graduating to primary endpointsConnected devices from consumer tech giants have been involved in clinical trials for years. Suddenly, these devices can serve not only as exploratory or supportive endpoints, but can also be used for pivotal clinical trials. Hybrid and remote trial models run more smoothly if the devices feeding data into regulatory submissions are already validated by regulators.