Arenado hammered a fastball up in the zone from Gabriel Hughes over the left-field fence for his eighth career grand slam and second of the season. Zack Littell (1-0) made his D-backs debut in relief, giving up two hits and two walks over 4 2/3 innings. The only major blemish in Arizona’s win was that shortstop Geraldo Perdomo left the game after the fourth inning with left knee soreness. Hughes (0-4) gave up seven runs on five hits and three walks over four innings. Up nextThe Diamondbacks start LHP Mitch Bratt (1-1, 3.90 ERA) on Tuesday night vs. Rockies RHP Tomoyuki Sugano (11-5, 4.51).