HEALTH FIRST Emmy-Winning Actress Drops 63 Pounds After Taking GLP-1 The “This Is Us” star has lost a significant amount of weight while taking the medication. Kevin Winter/Getty ImagesEmmy-nominated actress Chrissy Metz got on a popular GLP-1 weight loss drug and lost over 60 pounds. “I had to do what I felt is best for me,” Metz, 45, told E! According to Ro’s website, Metz has lost 63 pounds since beginning treatment. In addition to taking the medicine, Metz also told People she is working on building more muscle with a trainer without an ideal weight in mind.