Programming membrane transport with a DNA origami nanosyringe A DNA origami nanosyringe introduces mechanically controlled molecular transport into synthetic cells. They present their DNA origami nanosyringe in Nature Nanotechnology ("A programmable DNA origami nanosyringe for directed membrane translocation"). Right: DNA origami nanosyringe at the nanoscale for directed membrane translocation. The nanosyringe consists of two modular DNA origami components: a membrane-anchoring base and a movable needle connected through a reversible sliding mechanism. These demonstrations show that mechanical membrane transport can directly regulate downstream biochemical functions with precise temporal control.