In a single-site study, it reduced Insomnia Severity Index scores by an average of 65%, with all participants seeing symptom improvement. Key takeaways:In a study of 37 adult patients, the Vida oral appliance reduced Insomnia Severity Index scores by an average of 65%, with 100% of participants improving by at least one classification level. Unpublished clinical data shows that treatment with Vivos Therapeutics Inc’s Vida oral appliance led to a statistically significant improvement in insomnia severity in 100% of study participants, according to Vivos. Insomnia severity was defined by the validated Insomnia Severity Index (ISI). While related home EEG testing may receive insurance reimbursement, the Vida appliance treatment is not typically reimbursed by most insurance carriers and would thus be paid for out of pocket.