How Chrissy Metz is starting a new chapter with GLP-1sThis morning on the Today show, Metz shared that she’s partnering with Ro to use GLP-1 medication—a decision she didn’t make on a whim. The 2010 transformation that started it allLong before GLP-1s were part of the conversation, Metz’s weight loss story captured headlines. I don’t really know,” she said. “Such rapid weight loss is not sustainable or safe for most people,” says Michael Koehler, MD, medical director at Affinity Whole Health. Doing what’s right for herWhen asked how she’d respond to anyone disappointed about her GLP-1 decision, Metz didn’t hesitate.