New research suggests weight-loss drugs, such as semaglutide and tirzepatide, are being used by some high-level athletes without a medical need, raising questions about their effect on performance and athlete health. One in 10 said they were aware of athletes using weight-loss drugs without a medical reason. Low energy availability issues for runnersGLP-1 drugs mimic a hormone involved in blood-sugar control and appetite. Track and field already has a well-documented problem with low energy availability. The agency is also supporting research into improved methods for detecting GLP-1 drugs in athletes.