Read our Privacy noticeCardiovascular-kidney-metabolic syndrome, or CKM syndrome, affects millions of Americans - but many may not know what signs to watch out for. Some 90 percent of Americans have at least one risk factor for CKM syndrome, such as excess body fat, high cholesterol and high blood pressure. open image in gallery Our diet, exercise and sleep can put us at risk for health issues involving our heart, metablic and kidney health, such as CKM syndrome. The big threeBut eating a healthy and balanced diet, exercising enough and getting enough sleep can help people stave off obesity and reverse CKM syndrome symptoms. Disease in stagesWhen you catch signs of CKM syndrome is also important.