Unfortunately for James Jr., his sophomore season in 2016 was cut short, with him suffering a lateral meniscus tear and cartilage damage, effectively ending his season. James Jr. still recorded an interception in the two games he appeared in. Minter instantly had a plan for James Jr., giving him a simplified role, a role that fit the 28-year-old safety. James Jr. earned another All-Pro selection, being a part of the second team. James Jr. is expected to continue to lead this Chargers defense, setting the tone for what the standard is of being a "Charger".