When it comes to choosing what airline to book for your next vacation, there are all kinds of considerations. But if you're looking for the best of the best for an American domestic airline, book a seat with JSX. It was ranked the "Best Domestic Airline" by Travel+Leisure in 2026, 2025, and 2024 for their "World's Best Awards." None of America's major carriers — American, Delta, United, and Southwest Airlines — made the top three, and Delta came in at No. You can drive up to the terminal within an hour of your flight, potentially as little as 20 minutes before a domestic flight.