This week, the 2026 QSR 50 was released, giving the industry a rundown on who’s on top and who’s not. Here are the 10 largest fast-food chains in America, ranked by the latest QSR data. Q1 2026 same-store sales increased 0.5%, including a 0.6% increase in transactions, while digital sales reached $1.2 billion in Q1, representing 38.6% of sales. StarbucksStarbucks, in the midst of a major turnaround with a new CEO at the helm, remains America’s second-largest QSR by systemwide sales. McDonald’sMcDonald’s is still America’s largest fast-food/QSR chain by systemwide sales.