Scientists have raised concerns about biosecurity after artificial intelligence (AI) was used to design new viruses. In their commentary, the pair of doctors responded to the results of a study in which a team of researchers used AI to design bacteriophages. The ability to compose viral genomes using generative AI now exists; the governance to safely steer it does not,” Inglesby and Hanke wrote in the commentary piece. The doctors also questioned whether generative viral genome design can be used without “enabling serious harm.” The team used genome language models Evo 1 and Evo 2 to generate phage genomes for E. coli bacteria.