What to ConsiderFirst and foremost, not everyone needs an electrolyte powder (or an electrolyte drink ) every day. Some electrolyte powders have no carbohydrates, while others may contain 15 grams or more. FAQsWhen Is the Best Time to Use Electrolyte Powders? Are There Any Side Effects Associated With Electrolyte Powders? Depending on the ingredients, some electrolyte powders could lead to digestive upset, especially if they include high amounts of sugar, sugar alcohol, or magnesium.