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Drug-Induced Autoimmune Inflammatory Myositis in a Patient with Psoriatic Arthritis Receiving Biologic Therapy: A Case Report
['G. Anantha Lakshmi', 'Department Of Pharmacy Practice', 'Sri Venkateshwara College Of Pharmacy', 'Hyderabad', 'Kata Akshitha Goud', 'Mohammed Zabeer Uddin', 'Vinjamuri Bhavya Sri', 'Fabio Van Paris', 'Correspondence To']
European Medical Journal
Drug-induced autoimmune myositis is an increasingly recognized entity, particularly in patients receiving biologic and targeted immunomodulatory therapies, which may disrupt immune homeostasis and trigger inflammatory muscle injury.
Based on clinical and biochemical findings, a diagnosis of autoimmune inflammatory myositis was established.
This case underscores the importance of recognizing autoimmune inflammatory myositis as a potential complication of biologic therapy and highlights the need for early diagnosis and vigilant monitoring in patients receiving long-term immunomodulationKey Points: 1.
2.This case report describes a patient with psoriatic arthritis who developed autoimmune inflammatory myositis after prolonged sequential exposure to multiple biologic and targeted therapies, highlighting the diagnostic challenge of distinguishing drug-induced myositis from disease progression and other potential causes.
Based on the patient’s clinical presentation, physical examination findings, and biochemical evidence of muscle injury, a diagnosis of autoimmune inflammatory myositis was established.