Brandon Aiyuk's best opportunity to play NFL football again went out the window the moment the Washington Commanders signed Stefon Diggs on Wednesday. A brief history of Brandon Aiyuk's career-busting anticsAiyuk suffered a serious knee injury during the 2024 campaign with the San Francisco 49ers, which kept him out long-term into 2025. Brandon Aiyuk's NFL future is in serious limbo after Commanders sign Stefon DiggsIn the simplest technical terms, Brandon Aiyuk is not allowed to play in the NFL in 2026. When the 49ers placed him on the "left squad" list, he literally became ineligible to participate — even for San Francisco. It didn't have to be this way, Brandon.