And if you’re looking at the benefits of intermittent fasting for women over 50, there are a range to choose from. But for women over 50 in particular, is intermittent fasting safe? Intermittent fasting is generally safe for women over 50, but everyone is different. Possible benefits of intermittent fasting over 50Despite the challenges, there are a few perks you’ll likely enjoy if you try intermittent fasting over 50. Research has found that intermittent fasting may be as effective as calorie-restricted diets for weight loss.