That being said, what is Indiana's most dangerous animal? Get our free mobile appIndiana's Most Dangerous Animal: Exhibit AExplored Planet took a deep dive and looked at the most menacing creatures in America and came up with The Most Dangerous Animal In Each State. According to Explored Planet, the most dangerous animal in Indiana is one of those cute animals that are deceptively dangerous. Indiana's Most Dangerous Animal: Exhibit BThe 2026 report from World Population Review revealed the most dangerous animal in each state. When it comes to Indiana, the eastern copperhead is our most dangerous animal.