The Toyota Sienna Isn't Cheap, And That's Not Bad2025 Toyota Sienna Platinum front 3/4 angle in gray ToyotaAt its most basic, the Sienna isn't too expensive. 2026 Lexus RX 350 Premium AWD front 3/4 LexusBuyers with a nearly $60k budget have plenty of choices, though. Only The Sienna Can Return Fuel Economy This Good2025 Toyota Sienna Platinum Rear Angle on School Run ToyotaAll 2026 Toyota Siennas are powered by a naturally aspirated 2.5-liter inline-four-cylinder hybrid system that makes 245 combined horsepower. More Space For People And Cargo2025 Toyota Sienna Platinum interior view of the second row ToyotaSo the Lexus RX can technically match the Sienna's fuel economy, but it can't replicate the Sienna's interior space and practicality. 2025 Lexus RX Interior view of the second row LexusThe picture above shows the rear seats in a Lexus RX.